Beauty and Health

Combining GLP-1s with Other Cosmetic Treatments Safely

BY BLISS TEAM,  
June 18, 2025

GLP-1 medications like Ozempic, Wegovy, and Mounjaro have sparked major conversations, not just in the world of weight management, but in aesthetic medicine too. As more people achieve significant body changes with these medications, many are asking the next question:

Can I safely combine GLP-1s with other aesthetic treatments? Short answer: yes, but with the right strategy, timing, and care.

At Bliss, we’re seeing more patients curious about how to approach cosmetic surgery, injectables, and skin treatments while on GLP-1s. Here's what you need to know and how our smart-matching tech and Care Advisor support can guide your journey.

What Are GLP-1s?

Let’s start with the basics. Put simply, GLP-1 receptor agonists are a class of medications originally developed for type 2 diabetes that are now FDA-approved for weight loss. They work by:

  • Slowing gastric emptying.
  • Reducing appetite.
  • Helping regulate blood sugar.

Medications like Ozempic and Wegovy have become widely used by people looking to lose weight in a medically supervised way. But with weight loss often comes significant changes in the face and body, which can spark interest in surgical or nonsurgical treatments to address volume loss, skin laxity, or proportions.

How Weight Loss Affects Aesthetic Goals

GLP-1s are incredibly effective, but they can also lead to:

  • Facial volume loss (aka “Ozempic face”),
  • Loose or sagging skin in the abdomen, arms, and thighs,
  • Changes in body proportions that affect breast or buttock shape,
  • Among others, more unique concerns… 

While these changes are totally normal and expected with weight loss, they can shift what someone envisions for their ideal aesthetic result. That’s why timing and personalization are key when considering aesthetic treatments alongside GLP-1 use.

Can You Have a Cosmetic Procedure While on a GLP-1?

This is where things get specific and where expert guidance matters.

GLP-1s impede digestion, which can offer concerns during general anesthesia, such as aspiration (when stomach contents enter the lungs). As a result, many surgeons and anesthesiologists advise halting GLP-1 drugs 1 to 2 weeks before surgery.

If you're planning a procedure like a tummy tuck, facelift, or liposuction, you need to:

  • Disclose your medication regimen to your surgeon.
  • Coordinate with your prescribing physician before stopping or restarting the medicine.
  • Work with a team that knows the link between surgical planning and weight management.

At Bliss, we make sure your surgeon is thoroughly informed, and our Care Advisors can help you prepare for a safe experience from consultation to recovery.

When Is the Right Time to Pursue Surgery?

It’s important to remember that patience is key. If you’ve recently started GLP-1 therapy or are actively losing weight, many surgeons will recommend waiting until your weight has stabilized, typically for 3 to 6 months, before planning major procedures.

This helps ensure:

  • Your skin has had time to adjust.
  • Surgical results are more predictable and long-lasting.
  • You won’t need revisions later due to ongoing weight changes.

Once you’re stable, you can explore procedures like:

  • Facelift or fat grafting to restore facial volume.
  • Body lifts or tummy tucks to address loose skin.
  • Breast augmentation or lift to restore proportion.   

We match you with surgeons who specialize in post-weight-loss aesthetics, because not every surgeon has experience with these complex cases.

What About Injectables or Skin Treatments While on a GLP-1?

Non-surgical treatments like dermal fillers, Botox, or skin tightening procedures are safe while on GLP-1s, but your injector needs to be aware of your medication and your recent weight changes.

You may need:

  • More filler than usual to restore volume.
  • A new approach to facial balancing, especially if weight loss has changed your facial structure.
  • Treatments are spaced strategically to complement your ongoing progress.

At Bliss, we work with providers who understand these factors and help you get natural-looking results that match your evolving look.

The Bliss Approach: Coordinated, Customized, and Safe

Your journey is unique, and it deserves care that’s just as thoughtful. At Bliss, we bring together:

  • Smart matching technology that will match you with surgeons and aesthetic experts according to your goals, medical history, and skill level.
  • Care advisors who stay by your side to clarify options, prepare you for consultations, and encourage your recovery.
  • A network of recognized experts who understand how to safely interact with patients using GLP-1s.

Whether you're just starting weight loss medication or have already achieved tremendous benefits, we'll help you navigate the next steps with safety, clarity, and confidence.

Let’s Talk About What’s Right for You

Combining GLP-1s with aesthetic treatments isn’t one-size-fits-all. But with the right support, you can move forward confidently and safely. Open your Bliss profile today to get started with the right Care Advisor and personalized treatment plan. 

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